Download or read book Nitric Oxide, Cell Signaling, and Gene Expression written by Santiago Lamas and published by CRC Press. This book was released on 2005-11-01 with total page 453 pages. Available in PDF, EPUB and Kindle. Book excerpt: Since the nineteenth century, when engineers were using nitroglycerin to blow up rockbeds, and doctors were prescribing it to relieve angina, scientists have been exploring the incredible and often baffling behavior of nitric oxide. In the 1980s, researchers discovered that nitric oxide had the capacity to regulate vascular tone through cyclic GMP,