Search Results for: Oecd Guidelines For The Testing Of Chemicals Section 4 Test No 488 Transgenic Rodent Somatic And Germ Cell Gene Mutation Assays

Test No. 488: Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays

Test No. 488: Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays
Author :
Publisher : OECD Publishing
Total Pages : 16
Release :
ISBN-10 : 9789264122819
ISBN-13 : 9264122818
Rating : 4/5 (19 Downloads)
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Book Synopsis Test No. 488: Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays by : OECD

Download or read book Test No. 488: Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays written by OECD and published by OECD Publishing. This book was released on 2011-07-28 with total page 16 pages. Available in PDF, EPUB and Kindle. Book excerpt: This Test Guideline describes an in vivo assay that detects chemicals that may induce gene mutations. In this assay, transgenic rats or mice that contain multiple copies of chromosomally integrated plasmid or phage shuttle vectors are used. The ...


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Test No. 488: Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays
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Test No. 488: Transgenic Rodent Somatic and Germ Cell Gene Mutation Assays

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This Test Guideline describes an in vivo assay that detects chemicals that may induce gene mutations. In this assay, transgenic rats or mice that contain multip
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This Test Guideline describes an in vivo erythrocyte Pig-a gene mutation assay (hereafter called the Pig-a assay) which uses an endogenous mammalian gene, the p
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This Test Guideline describes an in vivo assay that detects chemicals that may induce gene mutations in somatic and germ cells. In this assay, transgenic rats o
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The mouse heritable translocation test detects structural and numerical chromosome changes in mammalian germ cells as recovered in first generation progeny. The