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A solution to the protein folding problem has eluded researchers for more than 30 years. The stakes are high. Such a solution will make 40,000 more tertiary str
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Proteins in living systems carry out a great variety of specific functions, each of which depends on the precise three-dimensional structure of a particular pro
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Covering experiment and theory, bioinformatics approaches, and state-of-the-art simulation protocols for better sampling of the conformational space, this volum
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Since the first attempts to model proteins on a computer began almost thirty years ago, our understanding of protein structure and dynamics has dramatically inc
The Protein Folding Problem and Tertiary Structure Prediction
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