Chicken Egg Yolk Antibodies, Production and Application

Chicken Egg Yolk Antibodies, Production and Application
Author :
Publisher : Springer Science & Business Media
Total Pages : 276
Release :
ISBN-10 : 3540666796
ISBN-13 : 9783540666790
Rating : 4/5 (96 Downloads)

Book Synopsis Chicken Egg Yolk Antibodies, Production and Application by : Rüdiger Schade

Download or read book Chicken Egg Yolk Antibodies, Production and Application written by Rüdiger Schade and published by Springer Science & Business Media. This book was released on 2000-09-04 with total page 276 pages. Available in PDF, EPUB and Kindle. Book excerpt: Polyclonal antibodies, widely used in research and diagnostics, are conventionally isolated from the blood of immunised mammals. The fact that antibodies can also be detected in the yolk of eggs laid by immunised hens, led to the development of the yolk antibody technology as an alternative method less stressful to animals. Hens can be kept under nearly natural conditions and antibodies be isolated from the eggs. Further, the IgY-technology has the advantage that avian antibodies can be produced against several antigens which do not induce a immune response in mammals. Protocols on how to keep and immunise hens and on the extraction, isolation and use of antibodies from yolk are described in detail in this manual. For their work on yolk antibodies the authors received the FISEA (International Foundation for the Substitution of Animal Experimentation, Luxembourg) prize in 1997.


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