The Next Generation in Membrane Protein Structure Determination

The Next Generation in Membrane Protein Structure Determination
Author :
Publisher : Springer
Total Pages : 188
Release :
ISBN-10 : 9783319350721
ISBN-13 : 3319350722
Rating : 4/5 (21 Downloads)

Book Synopsis The Next Generation in Membrane Protein Structure Determination by : Isabel Moraes

Download or read book The Next Generation in Membrane Protein Structure Determination written by Isabel Moraes and published by Springer. This book was released on 2016-08-23 with total page 188 pages. Available in PDF, EPUB and Kindle. Book excerpt: This book reviews current techniques used in membrane protein structural biology, with a strong focus on practical issues. The study of membrane protein structures not only provides a basic understanding of life at the molecular level but also helps in the rational and targeted design of new drugs with reduced side effects. Today, about 60% of the commercially available drugs target membrane proteins and it is estimated that nearly 30% of proteins encoded in the human genome are membrane proteins. In recent years much effort has been put towards innovative developments to overcome the numerous obstacles associated with the structure determination of membrane proteins. This book reviews a variety of recent techniques that are essential to any modern researcher in the field of membrane protein structural biology. The topics that are discussed are not commonly found in textbooks. The scope of this book includes: Expression screening using fluorescent proteins The use of detergents in membrane protein research The use of NMR Synchrotron developments in membrane protein structural biology Visualisation and X-ray data collection of microcrystals X-ray diffraction data analysis from multiple crystals Serial millisecond crystallography Serial femtosecond crystallography Membrane protein structures in drug discovery The information provided in this book should be of interest to anyone working in the area of structural biology. Students will find carefully prepared overviews of basic ideas and advanced protein scientists will find the level of detail required to apply the material directly to their day to day work. Chapters 4, 5, 6, 8 and 9 of this book are published open access under a CC BY 4.0 license at link.springer.com.


The Next Generation in Membrane Protein Structure Determination Related Books

The Next Generation in Membrane Protein Structure Determination
Language: en
Pages: 188
Authors: Isabel Moraes
Categories: Science
Type: BOOK - Published: 2016-08-23 - Publisher: Springer

DOWNLOAD EBOOK

This book reviews current techniques used in membrane protein structural biology, with a strong focus on practical issues. The study of membrane protein structu
Crystallization of Membrane Proteins
Language: en
Pages: 343
Authors: Hartmut Michel
Categories: Medical
Type: BOOK - Published: 2018-01-18 - Publisher: CRC Press

DOWNLOAD EBOOK

The precise knowledge of the structure of biological macromolecules forms the basis of understanding their function and their mechanism of action. It also lays
Molecular Biology of the Cell
Language: en
Pages: 0
Authors:
Categories: Cells
Type: BOOK - Published: 2002 - Publisher:

DOWNLOAD EBOOK

Structural Biology in Drug Discovery
Language: en
Pages: 1437
Authors: Jean-Paul Renaud
Categories: Medical
Type: BOOK - Published: 2020-01-09 - Publisher: John Wiley & Sons

DOWNLOAD EBOOK

With the most comprehensive and up-to-date overview of structure-based drug discovery covering both experimental and computational approaches, Structural Biolog
Protein Structural Biology in Biomedical Research, Part A
Language: en
Pages: 361
Authors: C. Woodward
Categories: Science
Type: BOOK - Published: 1998-01-16 - Publisher: Elsevier

DOWNLOAD EBOOK

Recent advances in protein structural biology, coupled with new developments in human genetics, have opened the door to understanding the molecular basis of man