Applications of Domino Transformations in Organic Synthesis, Workbench Edition
Author | : Scott A. Snyder |
Publisher | : Thieme Chemistry |
Total Pages | : 0 |
Release | : 2016-05-11 |
ISBN-10 | : 3132401633 |
ISBN-13 | : 9783132401631 |
Rating | : 4/5 (33 Downloads) |
Download or read book Applications of Domino Transformations in Organic Synthesis, Workbench Edition written by Scott A. Snyder and published by Thieme Chemistry. This book was released on 2016-05-11 with total page 0 pages. Available in PDF, EPUB and Kindle. Book excerpt: The rapid pace of evolution in domino, or cascade-based transformations has revolutionized the practice of chemical synthesis for the creation of natural products, designed molecules, and pharmaceuticals. Science of Synthesis: Applications of Domino Transformations in Organic Synthesis explores the topic thoroughly and systematically, serving as the basis for practical applications and future research. The 2-volume set presents the cutting-edge in terms of design, strategy, and experimental procedures, leading to multiple events being accomplished within a single reaction vessel. The content is organized by the core type of reaction used to initiate the event, be it a pericyclic reaction, a metal-mediated transformation, radical chemistry, or an acid-induced cascade among many others. Volume 1 covers polyene/cation-pi cyclizations, metathesis, radical, and metal-mediated reactions, and non-radical skeletal rearrangements. Volume 2 covers pericyclic reactions (Diels-Alder, sigmatropic shifts, ene reactions), dearomatizations, and additions to C-O/C-N multiple bonds.